Telix 污污漫畫s has signed a licence to obtain exclusive global rights for the development and commercialisation of radiolabelled forms of Company鈥檚 olaratumab antibody for cancer treatment and diagnosis.
Lilly originally developed olaratumab as a non-radiolabelled monoclonal antibody that acts on Platelet Derived Growth Factor Receptor Alpha (PDGFR伪).
With the worldwide licence, Telix could repurpose olaratumab as a targeting agent for cancer treatment and radiopharmaceutical imaging.
As per the deal, Telix will pay $5m (AU$6.7m) upfront to Lilly for the exclusive licence to the latter鈥檚 intellectual property linked to the radiolabelled olaratumab development.
Telix will have access to use the product in pre-clinical as well as early-phase clinical trials for potential diagnosis and treatment of cancers in humans.
Furthermore, on meeting pre-specified development, regulatory and commercial goals, Lilly is entitled to receive up to $225m (~AU$301m) in milestone payments from Telix, which will also make royalty payments on net product sales.
How well do you really know your competitors?
Access the most comprehensive Company Profiles on the market, powered by GlobalData. Save hours of research. Gain competitive edge.
Thank you!
Your download email will arrive shortly
Not ready to buy yet? Download a free sample
We are confident about the unique quality of our Company Profiles. However, we want you to make the most beneficial decision for your business, so we offer a free sample that you can download by submitting the below form
By GlobalDataIn the initial stage, Telix will focus on developing the antibody for soft tissue sarcoma (STS), a rare kind of cancer.
The deal also provides Lilly with an option to potentially obtain an exclusive licence to a Telix-developed radiolabelled companion diagnostic.聽
If Lilly decides to exercise the option, the company will make a payment of $5m (~AU$6.7m) to Telix. In addition, Telix is eligible for up to $30m (~AU$40.1m) in potential development milestone payments as well as royalty payments.
Telix Group CEO and managing director Dr Christian Behrenbruch said: 鈥淚n our pre-transaction diligence and research, we have identified that a radiolabelled version of olaratumab could be efficacious in patients with STS, particularly as it is a highly radiation-sensitive cancer.
鈥淲e anticipate that early clinical translation with a radiolabeled olaratumab as an imaging agent may also provide valuable clinical information as to whether this asset has potential therapeutic efficacy, demonstrating the advantage of Telix鈥檚 鈥榯heranostic鈥� approach.鈥�
